Product Name: Ku80 antibody [5C5]
Applications: ELISA, FACS, ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Unpurified
Full Name: X-ray repair complementing defective repair in Chinese hamster cells 5
Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Synonyms: KUB2 Antibody , KU86 Antibody , KARP1 Antibody , KU80 Antibody , XRCC5 Antibody , NFIV Antibody
Cellular Localization:
CAS NO: 65-29-2
Product: ETC-1002
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Purified recombinant fragment of human XRCC5 expressed in E. Coli.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Ascites, 0.03% sodium azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25053255?dopt=Abstract
