Product Name: Kv4.2 antibody [N1N3]
Applications: WB
Predicted Target Size: 71 kDa (note) (2)
Positive Controls: U87-MG
Form Supplied: Liquid
Concentration: 0.59 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: potassium voltage-gated channel, Shal-related subfamily, member 2
Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq]
Synonyms: KIAA1044 antibody, KV4.2 antibody, MGC119702 antibody, MGC119703 antibody, RK5 antibody, KCND2 antibody, voltage-sensitive potassium channel antibody, voltage-gated potassium channel subunit Kv4.2 antibody, potassium voltage-gated channel subfamily D member 2 antibody, voltage-gated potassium channel Kv4.2 antibody, “potassium voltage-gated channel, Shal-related subfamily, member 2 antibody”
Cellular Localization: Cell membrane; Multi-pass membrane protein , Cell projection , dendrite
CAS NO: 98079-52-8
Product: Wilforine
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Kv4.2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23407165?dopt=Abstract
