Product Name: Kv4.3 antibody [C2C3], C-term
Applications: WB
Predicted Target Size: 73 kDa (note) (3)
Positive Controls: IMR32 , U87-MG
Form Supplied: Liquid
Concentration: 0.88 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: potassium voltage-gated channel, Shal-related subfamily, member 3
Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq]
Synonyms: KCND3L antibody, KCND3S antibody, KSHIVB antibody, KV4.3 antibody, MGC142035 antibody, MGC142037 antibody, KCND3 antibody, potassium ionic channel Kv4.3 antibody, potassium voltage-gated channel subfamily D member 3 antibody, voltage-gated potassium channel Kv4.3 antibody, sha1-related potassium channel Kv4.3 antibody, voltage-gated potassium channel subunit Kv4.3 antibody, voltage-gated K+ channel antibody, “potassium voltage-gated channel, Shal-related subfamily, member 3 antibody”
Cellular Localization: Membrane; Multi-pass membrane protein , Cell membrane , sarcolemma
CAS NO: 24169-02-6
Product: Pseudobufarenogin
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Kv4.3. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23135729?dopt=Abstract