Product Name: L1CAM (150kDa subunit) antibody
Applications: IHC-P, WB
Predicted Target Size: 140 kDa (note) (4)
Positive Controls: U87-MG , SK-N-SH , IMR32 , SK-N-AS
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: L1 cell adhesion molecule
Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq]
Synonyms: NCAM-L1 Antibody , SPG1 Antibody , HSAS Antibody , N-CAM-L1 Antibody , CAML1 Antibody , MASA Antibody , N-CAML1 Antibody , S10 Antibody , CD171 Antibody , L1 cell adhesion molecule Antibody , HSAS1 Antibody , MIC5 Antibody , L1CAM Antibody
Cellular Localization: Cell membrane; Single-pass type I membrane protein
CAS NO: 745017-94-1
Product: FTI-277
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human L1CAM (150kDa subunit). The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23656780?dopt=Abstract
