Product Name: L1CAM antibody [UJ127]
Applications: IHC, IHC-P, IP, WB
Predicted Target Size:
Positive Controls: IMR-5 cells
Form Supplied: Liquid
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G purified
Full Name: L1 cell adhesion molecule
Background: The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.
Synonyms: CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1, N CAML1, NCAM L1, N CAM L1, NCAML1
Cellular Localization:
CAS NO: 389-08-2
Product: Dihydromyricetin
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Homogenous suspension of 16 week human fetal brain.
Antigen Species: Human
Species Reactivity: Human, Rat
Conjugation: Unconjugated
Storage Buffer: 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: GTX23200 is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin. It does not bind to pediatric or adult brain.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16293233?dopt=Abstract
