Product Name: LAIR1 antibody [NKTA255] (FITC)
Applications: FACS
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A purified
Full Name: leukocyte associated immunoglobulin like receptor 1
Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Synonyms: CD305 Antibody , LAIR-1 Antibody , leukocyte-associated immunoglobulin-like receptor 1 Antibody
Cellular Localization:
CAS NO: 82586-52-5
Product: Aloin B
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: NK cell lines B12.100 and AM.25
Antigen Species: Human
Species Reactivity: Human
Conjugation: FITC
Storage Buffer: PBS, 0.09% Sodium Azide, 1% BSA
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light. This product may contain precipitation. Recommend microcentrifugation before use.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody recognizes human leukocyte-associated Ig-like receptor-1 (LAIR1).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23639809?dopt=Abstract
