Product Name: LANA2 antibody [CM-A807]
Applications: ICC/IF, IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 8 mg/ml (Please refer to the vial label for the specific concentration)
Purification:
Full Name:
Background: LANA2 (latency-associated nuclear antigen) is an inhibitor of p53-induced transcription in reporter assays and may be an apoptosis antagonist. It is a nuclear protein associated with Kaposis sarcoma-associated herpes virus (KSHV), or human herpes virus 8. It is found in abundance in the nuclei of cultured cells from KSHV-infected hematopoietic tissues, such as PEL (primary effusion lymphoma) and CD (multicentric Castlemans disease). It does not appear to be expressed in KS (Kaposis sarcoma) lesions.
Synonyms: LANA-2 antibody, LANA 2 antibody, Latency-associated nuclear antigen 2 antibody
Cellular Localization: Nuclear
CAS NO: 88150-42-9
Product: (S)-Willardiine
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Fusion protein containing recombinant LANA2 protein.
Antigen Species:
Species Reactivity: Kaposis sarcoma-associated herpesvirus
Conjugation: Unconjugated
Storage Buffer: 0.1 ml of protein G purified mouse supernatant in PBS containing 0.1% sodium azide.
Storage Instruction: Store at 4ºC for short-term storage. Aliquot and store at -20°C for long-term. Avoid repeated freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for KSHV LANA2 (residues 143-310 epitope recognition).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24898855?dopt=Abstract