Product Name: LARGE antibody
Applications: IHC-P, WB
Predicted Target Size: 88 kDa (note) (3)
Positive Controls: mouse liver
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: like-glycosyltransferase
Background: This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]
Synonyms: MDDGB6 Antibody , MDC1D Antibody , MDDGA6 Antibody , like-glycosyltransferase Antibody
Cellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein
CAS NO: 16595-80-5
Product: UNC0379 (trifluoroacetate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human LARGE. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24231356?dopt=Abstract
