Product Name: LAT antibody, C-term
Applications: WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX17032-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: linker for activation of T cells
Background: Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.
Synonyms: pp36, LAT, linker for activation of T-cells family member 1, linker for activation of Tcells family member1, linker for activation of T cells, 36 kDa phospho-tyrosine adaptor protein, linker for activation of Tcells family member 1, LAT1, 36 kDa phosphotyrosine adaptor protein
Cellular Localization: Present in lipid rafts.
CAS NO: 51481-61-9
Product: BMH-21
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-GAPDYENLQELN
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for LAT.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19563916?dopt=Abstract
