Product Name: LC3B antibody [GT3612]
Applications: ICC/IF, WB
Predicted Target Size: 15 kDa (note)
Positive Controls: LC3B-transfected 293T , HepG2 (3 μM Thapsigargin treated for 12hr) , HeLa (50 μM chloroquine treated for 24hr)
Form Supplied: Liquid
Concentration: 0.43 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein A.
Full Name: microtubule-associated protein 1 light chain 3 beta
Background: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq]
Synonyms: MAP1A/1BLC3 Antibody , ATG8F Antibody , microtubule-associated protein 1 light chain 3 beta Antibody , MAP1LC3B-a Antibody , MAP1LC3B Antibody
Cellular Localization: Cytoplasm , Endomembrane system; Lipid-anchor , Cytoplasmic vesicle , autophagosome membrane; Lipid-anchor
CAS NO: 12542-36-8
Product: FICZ
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human LC3B. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24068925?dopt=Abstract
