Product Name: LDB2 antibody [N1C1]
Applications: WB
Predicted Target Size: 43 kDa (note) (5)
Positive Controls: HeLa , mouse brain
Form Supplied: Liquid
Concentration: 0.73 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: LIM domain binding 2
Background: Genes encoding LIM domain-binding factors were initially isolated in a screen for proteins that physically interact with the LIM domains of nuclear proteins (summarized by Semina et al., 1998 [PubMed 9799849]). These proteins, such as the one encoded by the LDB2 gene, are capable of binding to a variety of transcription factors and are likely to function at enhancers to bring together diverse transcription factors and form higher order activation complexes or to block formation of such complexes (Jurata and Gill, 1997 [PubMed 9315627]). The family of genes encoding LIM domain-binding factors includes 2 members isolated from the mouse, Clim1 (Bach et al., 1997 [PubMed 9192866]) and Clim2/Lbd1/Nli (Agulnick et al., 1996 [PubMed 8918878]; Jurata et al., 1996 [PubMed 8876198]; Bach et al., 1997 [PubMed 9192866]) and their homologs cloned from the frog, chicken, and fly. The fact that LIM domain-binding factors are likely to be involved in the coordination of the transcriptional activity of many diverse factors might implicate them in human phenotypes characterized by multiple affected sites.[supplied by OMIM]
Synonyms: CLIM1 antibody, LDB1 antibody, LDB2 antibody, LIM domain-binding factor-2 antibody, LDB-2 antibody, LIM domain-binding factor CLIM1 antibody, carboxyl-terminal LIM domain-binding protein 1 antibody, CLIM-1 antibody, LIM binding domain 2 antibody, LIM domain-binding protein 2 antibody, LIM domain binding 2 antibody
Cellular Localization: Nucleus
CAS NO: 129618-40-2
Product: CAY10603
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human LDB2. The exact sequence is proprietary.
Antigen Species:
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23478297?dopt=Abstract
