Product Name: LDHA antibody [AT1A4]
Applications: ELISA, FACS, ICC/IF, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: By protein-G affinity chromatography
Full Name: lactate dehydrogenase A
Background: Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle.
Synonyms: L-lactate dehydrogenase A chain Cell proliferation-inducing gene 19 protein, Renal carcinoma antigen NYREN59., Proliferationinducing gene 19, M LDH, Proliferationinducing gene19, Llactate dehydrogenase A chain Cell proliferationinducing gene 19 protein, Llactate dehydrogenase A chain Cell proliferationinducing gene19 protein, Lactate dehydrogenase A4
Cellular Localization:
CAS NO: 797-63-7
Product: Rupatadine (Fumarate)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2b
Immunogen: Recombinant human LDHA (1-332aa) purified from E.coli
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: In Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Storage Instruction: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19767061?dopt=Abstract
