Product Name: LEMD3 antibody
Applications: ELISA, ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity Chromatography Purified Via Peptide Column.
Full Name: LEM domain containing 3
Background: This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]
Synonyms: MAN1 Antibody , LEM domain containing 3 Antibody
Cellular Localization:
CAS NO: 97-77-8
Product: ESI-09
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: LEMD3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LEMD3.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide.
Storage Instruction: Stored At 4ºc For Three Months And -20ºc, Stable For Up To One Year. As With All Antibodies Care Should Be Taken To Avoid Repeated Freeze Thaw Cycles. Antibodies Should Not Be Exposed To Prolonged High Temperatures.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: At least three isoforms of LEMD3 are known to exist; this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/28486946?dopt=Abstract
