Product Name: LIGHT antibody [8C34]
Applications: FACS
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: tumor necrosis factor (ligand) superfamily, member 14
Background: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms: LTg Antibody , tumor necrosis factor (ligand) superfamily, member 14 Antibody , CD258 Antibody , LIGHT Antibody , HVEML Antibody , TR2 Antibody
Cellular Localization:
CAS NO: 143388-64-1
Product: Athidathion
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Human recombinant LIGHT EC domain
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to specifically detect human LIGHT.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21362503?dopt=Abstract
