Product Name: LILRB3 antibody [9S32]
Applications: FACS, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms: PIRB Antibody , LILRA6 Antibody , LIR3 Antibody , ILT-5 Antibody , HL9 Antibody , LIR-3 Antibody , leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 Antibody , LILRB3 Antibody , CD85A Antibody
Cellular Localization:
CAS NO: 1159101-48-0
Product: Novaluron
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2
Immunogen: Human recombinant LILRB3.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to detect human LILRB3.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27602110?dopt=Abstract
