Product Name: LILRB4 antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purification
Full Name: leukocyte immunoglobulin like receptor B4
Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms: leukocyte immunoglobulin like receptor B4 Antibody , HM18 Antibody , LILRB5 Antibody , ILT3 Antibody , LIR5 Antibody , CD85K Antibody
Cellular Localization:
CAS NO: 198821-22-6
Product: Tiadinil
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein of human LILRB4
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction: Store at -20℃. Avoid freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27827416?dopt=Abstract
