Product Name: LIMS1 antibody [C2C3], C-term
Applications: WB
Predicted Target Size: 37 kDa (note) (6)
Positive Controls: Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12 , Rat2
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: LIM and senescent cell antigen-like domains 1
Background: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq]
Synonyms: PINCH antibody, PINCH1 antibody, LIMS1 antibody, renal carcinoma antigen NY-REN-48 antibody, particularly interesting new Cys-His protein 1 antibody, LIM and senescent cell antigen-like-containing domain protein 1 antibody, LIM and senescent cell antigen-like domains 1 antibody
Cellular Localization: Cell junction , focal adhesion , Cell membrane; Peripheral membrane protein; Cytoplasmic side
CAS NO: 19387-91-8
Product: TAS-103 (dihydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LIMS1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24782865?dopt=Abstract
