Product Name: LITAF antibody [N1C3]
Applications: IHC-P, IP, WB, ChIP-seq
Predicted Target Size: 17 kDa (note) (2)
Positive Controls: HeLa , HepG2
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: lipopolysaccharide-induced TNF factor
Background: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Pagets disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Synonyms: FLJ38636 antibody, MGC116698 antibody, MGC116700 antibody, MGC116701 antibody, MGC125274 antibody, MGC125275 antibody, MGC125276 antibody, PIG7 antibody, SIMPLE antibody, TP53I7 antibody, LITAF antibody, LPS-induced TNF-alpha factor antibody, p53-induced gene 7 protein antibody, tumor protein p53 inducible protein 7 antibody, lipopolysaccharide-induced TNF-alpha factor antibody, lipopolysaccharide-induced tumor necrosis factor-alpha factor antibody, small integral membrane protein of lysosome/late endosome antibody, lipopolysaccharide-induced TNF factor antibody
Cellular Localization: Lysosome membrane; Peripheral membrane protein; Cytoplasmic side
CAS NO: 91161-71-6
Product: Oxybenzone
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24744315?dopt=Abstract
