Product Name: Lamin B1 antibody
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 66 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purification
Full Name: lamin B1
Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010]
Synonyms: LMNB Antibody , LMN Antibody , lamin B1 Antibody , ADLD Antibody , LMNB1 Antibody , LMN2 Antibody
Cellular Localization:
CAS NO: 70024-40-7
Product: GLPG0492
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein of human LMNB1
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction: Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22253829?dopt=Abstract
