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Product Name: Latrophilin 2 antibody [C3], C-term
Applications: ELISA-Ag
Predicted Target Size: 163 kDa (note)
Positive Controls: Synthetic peptide: 1:8,000
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: latrophilin 2
Background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. While several transcript variants have been described, the biological validity of only one has been determined. [provided by RefSeq]
Synonyms: CIRL2 antibody, CL2 antibody, LEC1 antibody, LPHH1 antibody, LPHN2 antibody, calcium-independent alpha-latrotoxin receptor 2 antibody, lectomedin-1 antibody, latrophilin homolog 1 antibody, latrophilin homolog 2 (cow) antibody, latrophilin-2 antibody, latrophilin 1 antibody, CIRL-2 antibody, latrophilin 2 antibody
Cellular Localization: Cell membrane; Multi-pass membrane protein
CAS NO: 53716-50-0
Product: PRT062607
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Latrophilin-2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity:
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18791645?dopt=Abstract

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