Product Name: Leptin antibody [11] (Biotin)
Applications: ELISA
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Biotinylated
Full Name: leptin
Background: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
Synonyms: leptin Antibody , LEP Antibody
Cellular Localization:
CAS NO: 135463-81-9
Product: LCZ696
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant human leptin
Antigen Species: Human
Species Reactivity:
Conjugation: Biotin
Storage Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
Storage Instruction: 4-8ÂșC without exposure to light. No precautions necessary during handling.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody binds human leptin.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26320173?dopt=Abstract
