Product Name: Leptin antibody [BDI170], C-term
Applications: IHC-Fr, IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Unpurified
Full Name:
Background: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
Synonyms: LEP Antibody
Cellular Localization:
CAS NO: 244767-67-7
Product: Avatrombopag
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: Synthetic human leptin (131-145) attached to a carrier protein
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Ascites
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Binds to the carboxyl terminal region of the protein and to the intact leptin specifically in ELISA,Western blot and immunocytochemistry.Cross-reactivity:Leptin (Human) 100% Leptin (131-145) 100% Epidermal Growth Factor (Human) 0% Insulin (Human) 0% Insulin-like Growth Factor 1 (Human) 0% Insulin-like Growth Factor 2 (Rat) 0% Parathyroid hormone (Human) 0% Transforming Growth Factor-alpha (Human) 0%
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24590176?dopt=Abstract
