Product Name: Lewis B antibody [T218]
Applications: IHC-P
Predicted Target Size:
Positive Controls: Colon adenocarcinoma (human).
Form Supplied: Liquid
Concentration:
Purification: Purified IgM
Full Name:
Background: Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. Increased expression of Lewis B has been reported in gastric and pancreatic tumors, as well as in colorectal cancer.
Synonyms: MUC5, TBM, leB
Cellular Localization:
CAS NO: 287714-41-4
Product: Pifithrin-β (hydrobromide)
Host: Mouse
Clonality: Monoclonal
Isotype: IgM
Immunogen: SK-CO-10 colon cancer cell line (Human).
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Preservative: 0.1% Sodium Azide; Constituents: 1% BSA, PBS
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody detects Lewis B (Type 1 chain) and belongs to the BG-6 group, one of a series of well-characterized murine monoclonal antibodies detecting blood group specificities of the ABH and Lewis systems.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23283981?dopt=Abstract
