Product Name: Livin antibody [1B10]
Applications: FACS, ICC/IF, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Protein A/G purified
Full Name: baculoviral IAP repeat containing 7
Background: Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
Synonyms: MLIAP, KIAP, RNF50, LIVIN, ML-IAP, BIRC7, ML IAP
Cellular Localization: Nuclear, and in a filamentous pattern throughout the cytoplasm.
CAS NO: 56-85-9
Product: Dafadine-A
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Full length human recombinant protein of human Livin (NP_071444) produced in HEK293T cell.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Instruction: For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: GTX84822 is specific for human Livin (NP_071444).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23063797?dopt=Abstract
