Product Name: Livin antibody, C-term
Applications: WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX89665-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: baculoviral IAP repeat containing 7
Background: Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
Synonyms: melanoma inhibitor of apoptosis protein, baculoviral IAP repeatcontaining 7 (livin), baculoviral IAP repeatcontaining protein 7, MLIAP, KIAP, RNF50, baculoviral IAP repeatcontaining protein7, livin inhibitorofapotosis, baculoviral IAP repeatcontaining7 (livin), livin inhibitor-of-apotosis, LIVIN, ML-IAP, livin inhibitor of ap, BIRC7, LIVIN / BIRC7, ML IAP, livin inhibitor of apotosis
Cellular Localization: Nuclear, and in a filamentous pattern throughout the cytoplasm.
CAS NO: 117467-28-4
Product: Tolazoline
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-RAPVRSRVRT
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for Livin.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20159561?dopt=Abstract
