Product Name: eIF2 alpha antibody [5D10]
Applications: ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Protein A/G purified
Full Name: eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Background: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Synonyms: EIF2S1, EIF2, EIF-2, EIF-2alpha, EIF2A, EIF-2A, EIF2alpha, EIF 2, EIF 2A, EIF 2alpha
Cellular Localization:
CAS NO: 278779-30-9
Product: E 2012
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Full length human recombinant protein of human EIF2S1 (NP_004085) produced in HEK293T cell.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Instruction: For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: GTX84583 is specific for human EIF2S1 (NP_004085).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22442066?dopt=Abstract
