Product Name: eNOS (phospho Ser1177) antibody
Applications: ICC/IF, IHC-P
Predicted Target Size: 140 (note)
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Full Name: nitric oxide synthase 3 (endothelial cell)
Background: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Synonyms: ECNOS, eNOS, NOS3, constitutive NOS, cNOS, NOS type III, endothelial NOS, EC-NOS, NOSIII, nitric oxide synthase, endothelial, nitric oxide synthase 3 (endothelial cell)
Cellular Localization:
CAS NO: 658084-23-2
Product: ONO-AE3-208
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen: Peptide sequence around phosphorylation site of serine 1177 (T-Q-S(p)-F-S) derived from Human eNOS.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25557405?dopt=Abstract
