Product Name :
R1487
Description:
R1487 is an orally bioavailable and highly selective inhibitor of p38α with an ic50 value of 10 nM.
CAS:
449808-64-4
Molecular Weight:
424.83
Formula:
C19H19ClF2N4O3
Chemical Name:
6-(2,4-difluorophenoxy)-8-methyl-2-[(oxan-4-yl)amino]-7H,8H-pyrido[2,3-d]pyrimidin-7-one hydrochloride
Smiles :
Cl.CN1C(=O)C(=CC2=CN=C(NC3CCOCC3)N=C12)OC1C=CC(F)=CC=1F
InChiKey:
RQHSAIGGUWVOBG-UHFFFAOYSA-N
InChi :
InChI=1S/C19H18F2N4O3.ClH/c1-25-17-11(10-22-19(24-17)23-13-4-6-27-7-5-13)8-16(18(25)26)28-15-3-2-12(20)9-14(15)21;/h2-3,8-10,13H,4-7H2,1H3,(H,22,23,24);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Thyrotropin} MedChemExpress|{Thyrotropin} Purity & Documentation|{Thyrotropin} References|{Thyrotropin} supplier|{Thyrotropin} Autophagy}
Additional information:
R1487 is an orally bioavailable and highly selective inhibitor of p38α with an ic50 value of 10 nM.{{Droxidopa} medchemexpress|{Droxidopa} Neuronal Signaling|{Droxidopa} Technical Information|{Droxidopa} Formula|{Droxidopa} supplier|{Droxidopa} Epigenetic Reader Domain} |Product information|CAS Number: 449808-64-4|Molecular Weight: 424.83|Formula: C19H19ClF2N4O3|Chemical Name: 6-(2,4-difluorophenoxy)-8-methyl-2-[(oxan-4-yl)amino]-7H,8H-pyrido[2,3-d]pyrimidin-7-one hydrochloride|Smiles: Cl.CN1C(=O)C(=CC2=CN=C(NC3CCOCC3)N=C12)OC1C=CC(F)=CC=1F|InChiKey: RQHSAIGGUWVOBG-UHFFFAOYSA-N|InChi: InChI=1S/C19H18F2N4O3.PMID:24914310 ClH/c1-25-17-11(10-22-19(24-17)23-13-4-6-27-7-5-13)8-16(18(25)26)28-15-3-2-12(20)9-14(15)21;/h2-3,8-10,13H,4-7H2,1H3,(H,22,23,24);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C). DMSO: Insoluble. Water: Insoluble.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
