Product Name :
Ivacaftor hydrate
Description:
VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a “potentiator” of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.
CAS:
1134822-07-3
Molecular Weight:
410.51
Formula:
C24H30N2O4
Chemical Name:
N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrate
Smiles :
O.{{Tebuconazole} site|{Tebuconazole} Apoptosis|{Tebuconazole} Protocol|{Tebuconazole} References|{Tebuconazole} custom synthesis|{Tebuconazole} Autophagy} CC(C)(C)C1=CC(=C(O)C=C1NC(=O)C1=CNC2=CC=CC=C2C1=O)C(C)(C)C
InChiKey:
MYELKYHBCRDZNH-UHFFFAOYSA-N
InChi :
InChI=1S/C24H28N2O3.H2O/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28;/h7-13,27H,1-6H3,(H,25,28)(H,26,29);1H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Tideglusib} medchemexpress|{Tideglusib} Stem Cell/Wnt|{Tideglusib} Biological Activity|{Tideglusib} Formula|{Tideglusib} custom synthesis|{Tideglusib} Autophagy}
Additional information:
VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR.PMID:24182988 Ivacaftor is a “potentiator” of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.|Product information|CAS Number: 1134822-07-3|Molecular Weight: 410.51|Formula: C24H30N2O4|Chemical Name: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrate|Smiles: O.CC(C)(C)C1=CC(=C(O)C=C1NC(=O)C1=CNC2=CC=CC=C2C1=O)C(C)(C)C|InChiKey: MYELKYHBCRDZNH-UHFFFAOYSA-N|InChi: InChI=1S/C24H28N2O3.H2O/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28;/h7-13,27H,1-6H3,(H,25,28)(H,26,29);1H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
