Product Name :
WHI-P154
CAS No.:
211555-04-3
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=CC2=NC=NC(=C2C=C1OC)NC3=CC=C(O)C(=C3)Br
Product Description :
WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.{{38966-21-1} medchemexpress|{38966-21-1} Technical Information|{38966-21-1} In stock|{38966-21-1} custom synthesis} 8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
Formula:
C16H14BrN3O3
Molecular Weight :
376.2
Synonyms:
Additional Information:
|CAS No.{{41451-75-6} medchemexpress|{41451-75-6} Protocol|{41451-75-6} In Vivo|{41451-75-6} supplier} 211555-04-3 ; |Formula C16H14BrN3O3 ; |Molecular Weight 376.PMID:29489192 2 ; |SMILES COC1=CC2=NC=NC(=C2C=C1OC)NC3=CC=C(O)C(=C3)Br ; |Product Description WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO
