Product Name :
PERK-IN-2
Description:
PERK-IN-2 is a potent PERK inhibitor with an IC50 of 0.2 nM.
CAS:
1337531-83-5
Molecular Weight:
437.42
Formula:
C23H18F3N5O
Chemical Name:
1-(5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indol-1-yl)-2-(2,3,5-trifluorophenyl)ethan-1-one
Smiles :
CN1C=C(C2=C(N)N=CN=C12)C1=CC=C2C(CCN2C(=O)CC2=CC(F)=CC(F)=C2F)=C1
InChiKey:
JCUSVFKWUQBVHH-UHFFFAOYSA-N
InChi :
InChI=1S/C23H18F3N5O/c1-30-10-16(20-22(27)28-11-29-23(20)30)12-2-3-18-13(6-12)4-5-31(18)19(32)8-14-7-15(24)9-17(25)21(14)26/h2-3,6-7,9-11H,4-5,8H2,1H3,(H2,27,28,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Sabizabulin} MedChemExpress|{Sabizabulin} Apoptosis|{Sabizabulin} Purity & Documentation|{Sabizabulin} Purity|{Sabizabulin} custom synthesis|{Sabizabulin} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Liarozole} MedChemExpress|{Liarozole} RAR/RXR|{Liarozole} TGF-beta/Smad|{Liarozole} Technical Information|{Liarozole} Formula|{Liarozole} supplier}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PERK-IN-2 is a potent PERK inhibitor with an IC50 of 0.2 nM.|Product information|CAS Number: 1337531-83-5|Molecular Weight: 437.42|Formula: C23H18F3N5O|Chemical Name: 1-(5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indol-1-yl)-2-(2,3,5-trifluorophenyl)ethan-1-one|Smiles: CN1C=C(C2=C(N)N=CN=C12)C1=CC=C2C(CCN2C(=O)CC2=CC(F)=CC(F)=C2F)=C1|InChiKey: JCUSVFKWUQBVHH-UHFFFAOYSA-N|InChi: InChI=1S/C23H18F3N5O/c1-30-10-16(20-22(27)28-11-29-23(20)30)12-2-3-18-13(6-12)4-5-31(18)19(32)8-14-7-15(24)9-17(25)21(14)26/h2-3,6-7,9-11H,4-5,8H2,1H3,(H2,27,28,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33262168 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PERK-IN-2 (0.03-0.3 μM; 2 hours) inhibits PERK autophosphorylation in A459 cells with IC50 value ranging from 0.03−0.1 μM.|Products are for research use only. Not for human use.|
