Share this post on:

Product Name :
hDHODH-IN-2

Description:
hDHODH-IN-2 is an analogue of the active metabolite of Leflunomide. hDHODH-IN-2 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory activity.

CAS:
183946-00-1

Molecular Weight:
304.34

Formula:
C19H16N2O2

Chemical Name:
(2Z)-N-{[1,1′-biphenyl]-4-yl}-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide

Smiles :
N#C/C(=C(/O)\C1CC1)/C(=O)NC1C=CC(=CC=1)C1C=CC=CC=1

InChiKey:
CAGGGMPTWTUYHZ-ZCXUNETKSA-N

InChi :
InChI=1S/C19H16N2O2/c20-12-17(18(22)15-6-7-15)19(23)21-16-10-8-14(9-11-16)13-4-2-1-3-5-13/h1-5,8-11,15,22H,6-7H2,(H,21,23)/b18-17-

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
hDHODH-IN-2 is an analogue of the active metabolite of Leflunomide. hDHODH-IN-2 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory activity.|Product information|CAS Number: 183946-00-1|Molecular Weight: 304.34|Formula: C19H16N2O2|Chemical Name: (2Z)-N-{[1,1′-biphenyl]-4-yl}-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide|Smiles: N#C/C(=C(/O)\C1CC1)/C(=O)NC1C=CC(=CC=1)C1C=CC=CC=1|InChiKey: CAGGGMPTWTUYHZ-ZCXUNETKSA-N|InChi: InChI=1S/C19H16N2O2/c20-12-17(18(22)15-6-7-15)19(23)21-16-10-8-14(9-11-16)13-4-2-1-3-5-13/h1-5,8-11,15,22H,6-7H2,(H,21,23)/b18-17-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ladiratuzumab} site|{Ladiratuzumab} Protocol|{Ladiratuzumab} In Vitro|{Ladiratuzumab} custom synthesis|{Ladiratuzumab} Autophagy} |Shelf Life: ≥12 months if stored properly.{{RIPA Lysis Buffer} site|{RIPA Lysis Buffer} TGF-beta/Smad|{RIPA Lysis Buffer} Biological Activity|{RIPA Lysis Buffer} In Vivo|{RIPA Lysis Buffer} custom synthesis} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32969333 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|hDHODH-IN-2 (Compound 42) inhibits rat and mouse DHODH with log(1/IC50) values of 5.83 and 5.80, respectively in self-organizing molecular field analysis (SOMFA).|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Share this post on: