Product Name :
Ibrutinib-MPEA
Description:
Ibrutinib-MPEA (Compound 20) is ibrutinib derivative. Ibrutinib is a covalent and irreversible inhibitor of Bruton’s tyrosine kinase (BTK) that has been used to treat haematological malignancies.
CAS:
1710768-30-1
Molecular Weight:
581.71
Formula:
C32H39N9O2
Chemical Name:
(2E)-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-4-[4-(2-aminoethyl)piperazin-1-yl]but-2-en-1-one
Smiles :
NC1=NC=NC2=C1C(=NN2[C@H]1CN(CCC1)C(=O)/C=C/CN1CCN(CCN)CC1)C1C=CC(=CC=1)OC1C=CC=CC=1
InChiKey:
RQQVGXHWCJBNPV-DSCGJTOLSA-N
InChi :
InChI=1S/C32H39N9O2/c33-14-17-39-20-18-38(19-21-39)15-5-9-28(42)40-16-4-6-25(22-40)41-32-29(31(34)35-23-36-32)30(37-41)24-10-12-27(13-11-24)43-26-7-2-1-3-8-26/h1-3,5,7-13,23,25H,4,6,14-22,33H2,(H2,34,35,36)/b9-5+/t25-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Tirapazamine} MedChemExpress|{Tirapazamine} Cell Cycle/DNA Damage|{Tirapazamine} Biological Activity|{Tirapazamine} Description|{Tirapazamine} supplier|{Tirapazamine} Cancer}
Additional information:
Ibrutinib-MPEA (Compound 20) is ibrutinib derivative.{{Vunakizumab} site|{Vunakizumab} Immunology/Inflammation|{Vunakizumab} Technical Information|{Vunakizumab} In Vitro|{Vunakizumab} custom synthesis|{Vunakizumab} Epigenetics} Ibrutinib is a covalent and irreversible inhibitor of Bruton’s tyrosine kinase (BTK) that has been used to treat haematological malignancies.PMID:33355041 |Product information|CAS Number: 1710768-30-1|Molecular Weight: 581.71|Formula: C32H39N9O2|Chemical Name: (2E)-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-4-[4-(2-aminoethyl)piperazin-1-yl]but-2-en-1-one|Smiles: NC1=NC=NC2=C1C(=NN2[C@H]1CN(CCC1)C(=O)/C=C/CN1CCN(CCN)CC1)C1C=CC(=CC=1)OC1C=CC=CC=1|InChiKey: RQQVGXHWCJBNPV-DSCGJTOLSA-N|InChi: InChI=1S/C32H39N9O2/c33-14-17-39-20-18-38(19-21-39)15-5-9-28(42)40-16-4-6-25(22-40)41-32-29(31(34)35-23-36-32)30(37-41)24-10-12-27(13-11-24)43-26-7-2-1-3-8-26/h1-3,5,7-13,23,25H,4,6,14-22,33H2,(H2,34,35,36)/b9-5+/t25-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 33.33 mg/mL (57.30 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
