Product Name :
Propafenone Hydrochloride
Description:
Propafenone Hydrochloride is a sodium channel protein inhibitor. Propafenone Hydrochloride is an inhibitor of AR.
CAS:
34183-22-7
Molecular Weight:
377.90
Formula:
C21H28ClNO3
Chemical Name:
1-2-[2-hydroxy-3-(propylamino)propoxy]phenyl-3-phenylpropan-1-one hydrochloride
Smiles :
Cl.CCCNCC(O)COC1=CC=CC=C1C(=O)CCC1C=CC=CC=1
InChiKey:
XWIHRGFIPXWGEF-UHFFFAOYSA-N
InChi :
InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Propafenone Hydrochloride is a sodium channel protein inhibitor. Propafenone Hydrochloride is an inhibitor of AR.|Product information|CAS Number: 34183-22-7|Molecular Weight: 377.90|Formula: C21H28ClNO3|Synonym:|Rytmonorm hydrochloride|Rythmol hydrochloride|Rythmol SR hydrochloride|SA-79 hydrochloride|Chemical Name: 1-2-[2-hydroxy-3-(propylamino)propoxy]phenyl-3-phenylpropan-1-one hydrochloride|Smiles: Cl.CCCNCC(O)COC1=CC=CC=C1C(=O)CCC1C=CC=CC=1|InChiKey: XWIHRGFIPXWGEF-UHFFFAOYSA-N|InChi: InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 33.33 mg/mL (88.20 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.DC-Chol Inhibitor |Shelf Life: ≥12 months if stored properly.Telaprevir In stock |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32809483 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Propafenone (hydrochloride) (SA-79 (hydrochloride)) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Propafenone works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitability of the cells. Propafenone is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib. Propafenone differs from the prototypical class Ic antiarrhythmic in that it has additional activity as a beta-adrenergic blocker which can cause bradycardia and bronchospasm.|References:|Sestito A, Molina E. Atrial fibrillation and the pharmacological treatment: the role of propafenone. Eur Rev Med Pharmacol Sci. 2012 Feb;16(2):242-53.Products are for research use only. Not for human use.|
