Product Name :
VU0080241
Description:
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM.
CAS:
393845-24-4
Molecular Weight:
321.42
Formula:
C19H23N5
Chemical Name:
1-[1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-3-methylpiperidine
Smiles :
CC1CN(CCC1)C1N=CN=C2C=1C=NN2C1=CC=C(C)C=C1C
InChiKey:
CLQVVBPDAXJGBV-UHFFFAOYSA-N
InChi :
InChI=1S/C19H23N5/c1-13-6-7-17(15(3)9-13)24-19-16(10-22-24)18(20-12-21-19)23-8-4-5-14(2)11-23/h6-7,9-10,12,14H,4-5,8,11H2,1-3H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM.|Product information|CAS Number: 393845-24-4|Molecular Weight: 321.42|Formula: C19H23N5|Chemical Name: 1-[1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-3-methylpiperidine|Smiles: CC1CN(CCC1)C1N=CN=C2C=1C=NN2C1=CC=C(C)C=C1C|InChiKey: CLQVVBPDAXJGBV-UHFFFAOYSA-N|InChi: InChI=1S/C19H23N5/c1-13-6-7-17(15(3)9-13)24-19-16(10-22-24)18(20-12-21-19)23-8-4-5-14(2)11-23/h6-7,9-10,12,14H,4-5,8,11H2,1-3H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (155.56 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.FX1 Apoptosis |Shelf Life: ≥12 months if stored properly.Ibuprofen Description |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32401466 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20): 5626-5630.Products are for research use only. Not for human use.|
