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April 27, 2017Updated April 27, 2017

acetylation by p300 inhibits the glycosylase activity of human NEIL2 while it stimulates the glycosylase activity of OGG1

1 min read

eotid metabolism Fatty acid metabolism, lipid metabolism IDH2 qq P48735 Mitochondria Isocytrate metabolism, tricarboxylic...

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April 27, 2017Updated April 27, 2017

The significance of this distribution pattern and the precise location within sucrose gradients wherein miRNAs exert their translation inhibitory function remain to be elucidated

igf 1r

1 min read

age 184 Average 139 Average 123 Average 151 The peptides are named by the...

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April 26, 2017Updated April 26, 2017

the early expression of VGCC subunits may be required for normal pancreatic b-cell development and in combination with other signals may trigger the further differentiation of endocrine and b-cell lineages

igf 1r

1 min read

lterations or junction dissolution in cells depleted of Smad4 after one day of TGFb...

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April 26, 2017Updated April 26, 2017

We isolated the coding sequence for human Pax4 by PCR from differentiated H7 EBs and inserted it into the pCAG vector upstream of an IRES linking it to the puromycin resistance gene

igf 1r

1 min read

nduced hESCs into PDX1-expressing cells. By testing out the optimal concentration and timing of...

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April 25, 2017Updated April 25, 2017

To control for day-to-day variability, paired T-tests were used to determine statistical significance

igf 1r

1 min read

es diluted in 1% BSA for 1 h at RT. Bacteria were then stained...

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April 25, 2017Updated April 25, 2017

These results coupled with observations noted above are consistent with the notion that SirT1-null mice burn stored lipids at rates in excess of those in normal animals

igf 1r

1 min read

Stem Cell Review Board. Prior to staining, the sections were fixed in 4% paraformaldehyde...

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April 24, 2017Updated April 24, 2017

Changes at these sites at the very least should be neutral to the fitness of the protein but may have a mild advantageous effect

igf 1r

1 min read

3 different concentrations for 24 h. Total NADPH content of the cells was measured...

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April 24, 2017Updated April 24, 2017

The repeats from different subfamilies retain a similar solenoidal fold and nonglobular horseshoe shape but differ by 3D structures of individual repeats

igf 1r

2 min read

1428 Trim29: tripartite motif-containing 29 Atf3: activating transcription factor 3 Mmp12: matrix metallopeptidase 12...

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April 21, 2017Updated April 21, 2017

the phosphorylation of TCR-f chain and ZAP70 were found to be decreased to a level similar to that of non-activated cells

igf 1r

1 min read

iate from similar numbers of weak and strong growth phenotypes. Carbon source utilization cluster...

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April 21, 2017Updated April 21, 2017

It is still unclear how the MCC:APC complex falls apart and how the APC:Cdc20 complex is formed afterwards

igf 1r

2 min read

the primary antibody or mouse isotype IgG control in Leica Primary antibody diluent was...